Association between low blood plasmalogen levels, post-mortem brain pathology, and dementia

July 27, 2016

Dr. Dayan Goodenowe describes the association between low blood plasmalogen levels, post-mortem brain pathology, and dementia

On July 26, 2016, Dr. Dayan Goodenowe, founder of Prodrome Sciences Inc., presented research results from 552 elderly persons at the Alzheimer’s Association International Conference in Toronto, Canada that show low blood plasmalogens prior to death are associated with a higher odds of dementia independent of the pathological state of the brain at death. These results support the hypothesis that neuronal membrane integrity is directly associated with dementia. In addition, data from 100 post-mortem brain biopsies was presented that showed that brain plasmalogen levels are more predictive of a diagnosis of Alzheimer’s disease than traditional Alzheimer’s-related pathology.

Plasmalogens are a type of lipid (fat) that your body uses to keep cellular membranes in good working order. They are especially important for neurons in your brain. When your membranes do not have enough of these lipid molecules, they become rigid and stop functioning properly. Dr. Goodenowe is the inventor of several patents relating to the role of plasmalogens in neurodegenerative diseases. 

Contact us for more information.

 

Keep in touch

©2019 Prodrome Sciences Inc.

Search